The World Health Organization (WHO) programme aims to ensure that vaccines are shared fairly among all nations.
Covax is aiming to deliver about two billion doses of Covid-19 vaccines globally by the end of the year.
A total of 600,000 doses of the vaccine developed by AstraZeneca and Oxford University arrived in Ghana’s capital Accra on Wednesday.
Vaccinations are expected to start there next week.
“The arrival of the Covid-19 vaccines into Ghana is critical in bringing the pandemic to an end,” they said.
The West African country has recorded more than 80,700 cases of coronavirus and 580 deaths since the pandemic began. These numbers are believed to fall short of the actual toll because of low levels of testing.
It told the BBC that Ghana was one of the countries selected to receive the first batch of vaccine doses “as it met the conditions precedent for receiving the vaccine”